Effect of chronic obstructive pulmonary disease and smoking on the outcome of COVID-19

A study has been published today as a fast-track article for the IJTLD, investigating the association between chronic obstructive pulmonary disease (COPD), smoking and the potential for poor outcomes in patients with COVID-19.

The COVID-19 pandemic has continued to spread worldwide, and although most people are asymptomatic or only display a mild, flu-like illness, a significant proportion develop a severe response. It is of great importance to find risk factors or comorbidities associated with severe COVID-19 to protect the vulnerable and allow for prudent resource allocation.

Due to the large number of smokers, a slight increase in risk would have a significant impact on public health. Also, COPD has been shown to increase the severity of COVID-19 and tobacco smoking is one of the leading causes of COPD.

This study performed a systematic literature search of the major databases and an analysis of the data. This systematic review and meta-analysis revealed that COPD and smoking were associated with poor outcomes in patients with COVID-19, and that the overall association with poor outcome was stronger for COPD than for smoking.

Read the full text for more information, including the acknowledgments and citations.

This is a fast-tracked article from the International Journal of Tuberculosis and Lung Disease (IJTLD), published by The Union to ensure that scientific research of immediate concern is shared as rapidly as possible. Find out more about submitting relevant papers on COVID-19.